Der Kaninchen Polyklonal Anti-HOMER3 Antikörper wurde für WB, IHC (p) und FACS validiert. Er ist geeignet, HOMER3 in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HOMER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human HOMER3.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Shimobayashi, Wagner, Kapfhammer: "Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth." in: Molecular neurobiology, (2015) (PubMed).
Target
HOMER3
(Homer Homolog 3 (Drosophila) (HOMER3))
Andere Bezeichnung
HOMER3
Hintergrund
HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. This protein binds numerous other proteins including group I metabotropic glutamate receptors,inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.