PMCH Antikörper (AA 94-122)

Produktnummer ABIN651719

Der Kaninchen Polyklonal anti-PMCH Antikörper wird verwendet zum Nachweis von PMCH in Proben von Human und Maus. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für PMCH Antikörper (AA 94-122) (ABIN651719)

Target: PMCH (Pro-Melanin-Concentrating Hormone (PMCH))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMCH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB21251

Produktdetails anti-PMCH Antikörper

Bindungsspezifität: AA 94-122

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PMCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of human PMCH.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PMCH

Target: PMCH (Pro-Melanin-Concentrating Hormone (PMCH))

Andere Bezeichnung: PMCH

Hintergrund: The melanin-concentrating hormone (MCH) is a cyclic neuropeptide isolated initially from salmon pituitary gland and later from rat hypothalamus (summarized by Nahon et al., 1992 [PubMed 1572663]). In mammals, MCH perikarya are confined largely to the lateral hypothalamus and zona incerta area with extensive neuronal projections throughout the brain, including the neurohypophysis. The anatomic distribution suggests a neurotransmitter or neuromodulator role for MCH in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. MCH and 2 other putative neuropeptides, NEI and NGE, are encoded by the same precursor and appear colocalized in nerve cells and in many instances within the projections. The precursor is designated pro-melanin-concentrating hormone (PMCH).

Molekulargewicht: 18679

Gen-ID: 5367

NCBI Accession: NP_002665

UniProt: P20382

Pathways: Carbohydrate Homeostasis, Feeding Behaviour