NAT8 Antikörper (AA 110-138)

Produktnummer ABIN651148

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NAT8 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für NAT8 Antikörper (AA 110-138) (ABIN651148)

Target: NAT8 (N-Acetyltransferase 8 (NAT8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB25556

Produktdetails anti-NAT8 Antikörper

Bindungsspezifität: AA 110-138

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NAT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-138 amino acids from the Central region of human NAT8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-NAT8 Antikörper (ABIN651148)

Ding, Dellisanti, Ko, Czajkowski, Puglielli: "The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides." in: The Journal of biological chemistry, Vol. 289, Issue 46, pp. 32044-55, (2014) (PubMed).

Ding, Ko, Pehar, Kotch, Peters, Luo, Salamat, Puglielli: "Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces ?-secretase (BACE1) levels and A? generation." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 8424-33, (2012) (PubMed).

Details zu NAT8

Target: NAT8 (N-Acetyltransferase 8 (NAT8))

Andere Bezeichnung: NAT8

Hintergrund: This protein, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene.

Molekulargewicht: 25619

Gen-ID: 9027

NCBI Accession: NP_003951

UniProt: Q9UHE5