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SOX2 Antikörper (pSer249)

Der Kaninchen Polyklonal Anti-SOX2-Antikörper wurde für DB validiert. Er ist geeignet, SOX2 in Proben von Human zu detektieren.
Produktnummer ABIN650873

Kurzübersicht für SOX2 Antikörper (pSer249) (ABIN650873)

Target

Alle SOX2 Antikörper anzeigen
SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reaktivität

  • 246
  • 140
  • 73
  • 21
  • 13
  • 11
  • 10
  • 10
  • 8
  • 8
  • 7
  • 7
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 185
  • 70
  • 2
Kaninchen

Klonalität

  • 162
  • 95
Polyklonal

Konjugat

  • 122
  • 14
  • 14
  • 10
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser SOX2 Antikörper ist unkonjugiert

Applikation

  • 166
  • 99
  • 93
  • 49
  • 45
  • 42
  • 40
  • 40
  • 30
  • 23
  • 22
  • 21
  • 16
  • 12
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dot Blot (DB)

Klon

RB27265
  • Bindungsspezifität

    • 60
    • 16
    • 16
    • 15
    • 15
    • 10
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer249

    Homologie

    M, Sh

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This Sox2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S249 of human Sox2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    DB: 1:500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

    Andere Bezeichnung

    Sox2

    Hintergrund

    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

    Molekulargewicht

    34310

    Gen-ID

    6657

    NCBI Accession

    NP_003097

    UniProt

    P48431

    Pathways

    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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