MUC1 Antikörper (pThr1224)
-
- Target Alle MUC1 Antikörper anzeigen
- MUC1 (Mucin 1 (MUC1))
-
Bindungsspezifität
- pThr1224
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser MUC1 Antikörper ist unkonjugiert
-
Applikation
- Immunofluorescence (IF), Dot Blot (DB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MUC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1224 of human MUC1.
- Klon
- RB16594
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MUC1 Primärantikörper
-
-
- Applikationshinweise
- IF: 1:10~50. DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
-
- Target
- MUC1 (Mucin 1 (MUC1))
- Andere Bezeichnung
- MUC1 (MUC1 Produkte)
- Synonyme
- CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
- Hintergrund
- MUC1 is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
- Molekulargewicht
- 122102
- Gen-ID
- 4582
- NCBI Accession
- NP_001018016, NP_001018017, NP_001037855, NP_001037856, NP_001037857, NP_001037858, NP_001191214, NP_001191215, NP_001191216, NP_001191217, NP_001191218, NP_001191219, NP_001191220, NP_00
- UniProt
- P15941
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
-