CrkL Antikörper (pTry207)

Produktnummer ABIN645839

Der Ziege not_set anti-CrkL Antikörper wird verwendet zum Nachweis von CrkL in Proben von Human, Maus und Ratte.

Kurzübersicht für CrkL Antikörper (pTry207) (ABIN645839)

Target: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Konjugat: Dieser CrkL Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-CrkL Antikörper

Bindungsspezifität: pTry207

Spezifität: The Goat anti-CRKL antibody detects protein derived from human recombinant protein and K562 lysate at various concentrations.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Produktmerkmale: Goat Anti-CRKL

Immunogen: Synthetic peptide with sequence C-KIFDPQNPDENE, from the C Terminus of the protein sequence according to NP_005198, was used as immunogen.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Supplied as 100µg of purified antibody 0.5mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Lagerung: -20 °C

Details zu CrkL

Target: CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))

Andere Bezeichnung: CRKL

Hintergrund: Anti-Crkl antibody is a 33kDa adaptor protein that has been shown to activate the RAS and JUN kinase signalling pathways. Also transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential, and may mediate the transduction of intracellular signals.

NCBI Accession: NP_005198

Pathways: Interferon-gamma Pathway, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor