MUC1 Antikörper

Produktnummer ABIN643712

Der Maus Monoklonal anti-MUC1 Antikörper wird verwendet zum Nachweis von MUC1 in Proben von Human. Er wurde validiert für FACS, IHC (p), IP und IHC (fro).

Kurzübersicht für MUC1 Antikörper (ABIN643712)

Target: MUC1 (Mucin 1 (MUC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MUC1 Antikörper

Verwendungszweck: Mouse Anti-Human Mucin 1

Spezifität: Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. DS-MB-01935 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. The dominant epitope recognized by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. DS-MB-01935 has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. This antibody also reacts weakly with sections of small intestine and colon.

Aufreinigung: Purified

Immunogen: Human breast cancer cell line ZR-75-1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu MUC1

Target: MUC1 (Mucin 1 (MUC1))

Andere Bezeichnung: CD227

Pathways: Negative Regulation of intrinsic apoptotic Signaling