Dieser Maus Monoklonal Antikörper detektiert spezifisch Fibroblasts, Epithelial Cells in FACS, IP und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.
DS-MB-03292 recognizes a 112 kD molecule expressed on the cell surface of human fibroblasts and epithelial cells. In peripheral blood the antibody stains myeloid cells and a very small number of lymphocytes. Studies upon the antigen have shown it to be sensitive to SDS, but resistant to trypsin, tunicamycin and collagenase.In immunohistological studies the antibody has also been found to bind to epithelium, myoepthelium, smooth muscle and some leucocytes. DS-MB-03292 has been shown to be useful as a cell membrane marker to characterize chondrocyte differentiation giving a positive reaction with dedifferentiated human chondrocytes, and negative with differentiated chondrocytes This product is routinely tested in flow cytometry on the KG1 cell line.