HCV E2 Antikörper (AA 384-665)

Produktnummer ABIN640224

Der Ziege not_set anti-HCV E2 Antikörper (ABIN640224) detektiert spezifisch HCV E2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Hepatitis C Virus (HCV).

Kurzübersicht für HCV E2 Antikörper (AA 384-665) (ABIN640224)

Target: HCV E2 (Hepatitis C Virus Envelope Protein E2 (HCV E2))

Reaktivität: Hepatitis C Virus (HCV)

Wirt: Ziege

Konjugat: Dieser HCV E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HCV E2 Antikörper

Bindungsspezifität: AA 384-665

Spezifität: E2 envelope protein

Produktmerkmale: Goat Anti-Hepatitic C Virus (HCV) E2 (aa 384-665)

Aufreinigung: Purified

Immunogen: Recombinant E2 (genotype 1a)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 4-5 mg/ml (OD280nm, E^0.1% = 1.4)

Buffer: 0.01M PBS, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu HCV E2

Target: HCV E2 (Hepatitis C Virus Envelope Protein E2 (HCV E2))

Substanzklasse: Viral Protein

Hintergrund: Uev1A, also designated Uev1, UBE2V1 (for ubiquitin-conjugating enzyme E2 variant 1) and CROC1, shows sequence similarity to other ubiquitin-conjugating enzymes, but lacks the conserved cysteine residue critical for their catalytic activity. Therefore, Uev1A does not have ubiquitin-conjugating activity in vitro. However, constitutive expression of exogenous Uev1A in colon carcinoma cells inhibits their capacity to differentiate upon confluence. Studies on recombinant Uev1A show that it localizes to the nucleus, excluding the nucleolar regions. Uev1A functions with TRAF6, a RING domain protein, to catalyze the synthesis of unique polyubiquitin chains linked through Lysine 63 of ubiquitin. The gene encoding Uev1A maps to human chromosome 20q13.2.