Der Kaninchen Polyklonal anti-PLGF Antikörper (ABIN640185) detektiert spezifisch PLGF in WB, ELISA und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
DS-PB-02730 is specific for human placental growth factor (PlGF), a dimeric glycoprotein and member of the vascular endothelial growth factor (VEGF) family, involved in angiogenesis, and the stimulation of endothelial cell proliferation and migration. The three isoforms PlGF-1, PlGF-2 and PlGF-3 are present in most placental tissues and act through binding to the VEGFR-1/FLT1 receptor. The involvement of PlGF in angiogenesis has made PlGF a focus area in the study of inflammatory diseases such as rheumatoid arthritis and psoriasis, and PlGF is used as a biochemical marker in cardiovascular disease, and also detected at reduced levels during preeclampsia.
Produktmerkmale
Cytokines/Chemokines/Growth Factors/Receptors
Aufreinigung
Purified
Immunogen
Antisera to human PlGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.