HPV16 E7 Antikörper

Produktnummer ABIN639902

Der Maus Monoklonal anti-HPV16 E7 Antikörper wird verwendet zum Nachweis von HPV16 E7 in Proben von Human Papillomavirus 16 (HPV-16). Er wurde validiert für WB und ELISA.

Kurzübersicht für HPV16 E7 Antikörper (ABIN639902)

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reaktivität: Human Papillomavirus 16 (HPV-16)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HPV16 E7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HPV16 E7 Antikörper

Verwendungszweck: Mouse Anti-HPV 16 Oncoprotein E7

Spezifität: DS-MB-03401 recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. DS-MB-03401 cross-reacts with both the monomer and dimer forms of the E7 protein of HPV-18.

Produktmerkmale: Bacterial/Fungal/Parasitic/Viral Antigens

Aufreinigung: Purified

Immunogen: Oncoprotein E7 from human papillomavirus 16.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA, Western Blotting

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu HPV16 E7

Target: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Substanzklasse: Viral Protein