APP Antikörper (AA 1-16)

Produktnummer ABIN6391362

Dieses Anti-APP-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von APP in WB und ELISA. Geeignet für Human.

Kurzübersicht für APP Antikörper (AA 1-16) (ABIN6391362)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser APP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Güteklasse: Verified

Produktdetails anti-APP Antikörper

Bindungsspezifität: AA 1-16

Verwendungszweck: Amyloid beta peptide (aa1-16)

Sequenz: DAEFRHDSGY EVHHQK

Spezifität: This antibody is expected to recognize all reported isoforms of APP (NP_000475.1, NP_958816.1, NP_958817.1, NP_001129601.1, NP_001129602.1) and to recognize all lengths of the Amyloid beta peptide.

Kreuzreaktivität: Rind (Kuh), Hund, Human, Schwein

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 75 kDa band observed in Human Brain (Cerebral and Frontal cortex) lysates (calculated MW of 78.7 kDa according to NP_958817.1 and 72.6 according to NP_001129601.1). Recommended concentration: 1-3 μg/mL. Primary incubation was 1 hour.

Peptide ELISA: antibody detection limit dilution 1:8000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Andere Bezeichnung: APP

Hintergrund: APP, amyloid beta (A4) precursor protein, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, OTTHUMP00000096096, PN-II, alzheimer disease amyloid protein, amyloid beta A4 protein, beta-amyloid peptide, cerebral vascular amyloid peptide, peptidase nexin-II,

Gen-ID: 351

NCBI Accession: NP_000475, NP_958816, NP_958817, NP_001129601, NP_001129602

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour