Fukutin Antikörper (AA 111-160)
Kurzübersicht für Fukutin Antikörper (AA 111-160) (ABIN6390175)
Target
Alle Fukutin (FKTN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 111-160
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Verwendungszweck
- Unconjugated Rabbit polyclonal to FKTN
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Spezifität
- FKTN Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- FKTN antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human FKTN protein.
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Kommentare
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Widely expressed with highest expression in brain, heart, pancreas and skeletal muscle. Expressed at similar levels in control fetal and adult brain, but is much reduced in Fukuyama-type congenital dystrophy (FCMD) brains. Expressed in migrating neurons, including Cajar-Retzius cells and adult cortical neurons, as well as hippocampal pyramidal cells and cerebellar Purkinje cells. No expression observed in the glia limitans, the subpial astrocytes (which contribute to basement membrane formation) or other glial cells. In the FCMD brain, neurons in regions with no dysplasia show fair expression, whereas transcripts are nearly undetectable in the overmigrated dysplastic region.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Fukutin (FKTN)
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Andere Bezeichnung
- FKTN
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Molekulargewicht
- 50 kDa
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Gen-ID
- 2218
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UniProt
- O75072
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Pathways
- Regulation of Carbohydrate Metabolic Process
Target
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