USP33 Antikörper

Produktnummer ABIN636996

Dieses Anti-USP33-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von USP33 in IHC (p). Geeignet für Human.

Kurzübersicht für USP33 Antikörper (ABIN636996)

Target: USP33 (Ubiquitin Specific Peptidase 33 (USP33))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP33 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-USP33 Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: USP33 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Anwendungsinformationen

Applikationshinweise: IHC-P: 5 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Details zu USP33

Target: USP33 (Ubiquitin Specific Peptidase 33 (USP33))

Andere Bezeichnung: USP33

Hintergrund: USP 33 is a deubiquitinating enzyme involved in various processes such as cellular migration and beta-2 adrenergicreceptor/ADRB2 recycling. It is involved in cell migration via its interaction with intracellular domain of ROBO1, leadingto regulation of Slit signaling. It also plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-proteincoupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2adrenergic receptor (ADRB2).

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling