Prostaglandin E Synthase Antikörper

Produktnummer ABIN636994

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Prostaglandin E Synthase in IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Prostaglandin E Synthase Antikörper (ABIN636994)

Target: Prostaglandin E Synthase (PTGES)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prostaglandin E Synthase Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Prostaglandin E Synthase Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: PTGES antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Anwendungsinformationen

Applikationshinweise: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Details zu Prostaglandin E Synthase

Target: Prostaglandin E Synthase (PTGES)

Andere Bezeichnung: PTGES

Hintergrund: Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.