GRM2 Antikörper

Produktnummer ABIN636930

Dieses Anti-GRM2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GRM2 in IHC (p). Geeignet für Human.

Kurzübersicht für GRM2 Antikörper (ABIN636930)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRM2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GRM2 Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: GRM2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Anwendungsinformationen

Applikationshinweise: IHC-P: 4 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Details zu GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Andere Bezeichnung: GRM2

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The receptors in group II, including mGluRs 2 and 3, and group III, including mGluRs 4, 6, 7, and 8, (with some exceptions) prevent the formation of cyclic adenosine monophosphate, or cAMP, by activating a G protein that inhibits the enzyme adenylyl cyclase, which forms cAMP from ATP.

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport