Aryl Hydrocarbon Receptor Antikörper

Produktnummer ABIN636854

Der Kaninchen Polyklonal anti-Aryl Hydrocarbon Receptor Antikörper wird verwendet zum Nachweis von Aryl Hydrocarbon Receptor in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (ABIN636854)

Target: Aryl Hydrocarbon Receptor (AHR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Aryl Hydrocarbon Receptor Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: AHR antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Anwendungsinformationen

Applikationshinweise: IHC-P: 15-20 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Details zu Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Andere Bezeichnung: AHR

Hintergrund: The Aryl hydrocarbon receptor (AhR or AHR) is a member of the family of basic-helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. Upon ligand binding to chemicals such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the chaperones dissociate resulting in AhR translocating into the nucleus and dimerizing with ARNT (AhR nuclear translocator), leading to changes in gene transcription.

Pathways: Regulation of Cell Size