Der Kaninchen Polyklonal anti-GPR3 Antikörper (ABIN636774) detektiert spezifisch GPR3 in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
GPR3
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
IHC-P: 40 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target
GPR3
(G Protein-Coupled Receptor 3 (GPR3))
Andere Bezeichnung
GPR3
Hintergrund
GPR3 activates adenylate cyclase in the absence of ligand. GPR3 is expressed in mammalian oocytes where it maintains meiotic arrest and is thought to be a communication link between oocytes and the surrounding somatic tissue. It has been proposed that sphingosine 1-phosphate (S1P) and sphingosylphosphorylcholine (SPC) are GPR3 ligands, however this result was not confirmed in a Beta-arrestin recruitment assay.