Dinitrophenol Antikörper

Produktnummer ABIN636762

Zitiert in 1 Publikation. Der Ziege Polyklonal anti-Dinitrophenol Antikörper (ABIN636762) detektiert spezifisch Dinitrophenol in ELISA und WB.

Kurzübersicht für Dinitrophenol Antikörper (ABIN636762)

Target: Dinitrophenol (DNP)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Dinitrophenol Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Dinitrophenol Antikörper

Immunogen: Dinitrophenol antibody was raised in goat using dinitrophenol-modified protein as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen für anti-Dinitrophenol Antikörper (ABIN636762)

Fan, Schrott, Snelling, Felty, Graham, McGauly, Arnold, Korneeva: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).

Details zu Dinitrophenol

Target: Dinitrophenol (DNP)

Andere Bezeichnung: DNP

Substanzklasse: Chemical

Hintergrund: Tissues are continually exposed to reactive oxygen species (ROS) that are produced in tissues from metabolism processes or the inflammatory response of leukocytes or macrophages. It is estimated that as much as 1 % of consumed oxygen may be converted to ROS, which can cause damage to various cellular components. Proteins are one of the cellular components most vulnerable to oxidative damage by ROS, which results in an increase in protein carbonyl content. This oxidative modification of proteins can lead to cross-linking, peptide fragmentation, modified residues and the conversion of one amino group to another. If sufficient protein damage accumulates, cell death will occur.