AGE Antikörper

Produktnummer ABIN636761

Produktdetails anti-AGE Antikörper

Target: AGE (Advanced Glycation End Products (AGE))

Reaktivität: Bitte anfragen

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser AGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: AGE antibody was raised in goat using glycoaldehyde-modified protein as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu AGE

Target: AGE (Advanced Glycation End Products (AGE))

Andere Bezeichnung: AGE (AGE Produkte)

Synonyme: RBP antikoerper, RNBP antikoerper, renin binding protein antikoerper, RENBP antikoerper

Substanzklasse: Chemical

Hintergrund: Glycation is a post-translational modification of proteins involving a covalent linkage between a reducing sugar, such as glucose, and a receptive amino group via the non-enzymatic Maillard reaction. During the early stages of the Maillard reaction, the aldehyde groups of the reducing sugars react with the amino groups of N-terminal amino acids to form Schiff bases, which are then converted to Amadori compounds. In the advanced stages, these Amadori compounds undergo oxidation, dehydration and condensation to form advanced glycation end-products (AGE) that are characterized by fluorescence, browning, and intra- or inter-molecular cross-linking properties. The main AGE products are pentosine and carboxymethyllysine (CML).