MIA Antikörper

Produktnummer ABIN636661

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MIA in ELISA, WB und Inhibition. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MIA Antikörper (ABIN636661)

Target: MIA (Melanoma Inhibitory Activity (MIA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIA Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Blocking Antibody (Inhibition)

Produktdetails anti-MIA Antikörper

Aufreinigung: Purified

Immunogen: MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu MIA

Target: MIA (Melanoma Inhibitory Activity (MIA))

Andere Bezeichnung: MIA

Hintergrund: MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

Molekulargewicht: 12.2 kDa (predicted detection band MW)