RELM alpha Antikörper

Produktnummer ABIN636644

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-RELM alpha Antikörper wird verwendet zum Nachweis von RELM alpha in Proben von Maus. Er wurde validiert für WB, ELISA und Inhibition.

Kurzübersicht für RELM alpha Antikörper (ABIN636644)

Target: RELM alpha

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RELM alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Produktdetails anti-RELM alpha Antikörper

Aufreinigung: Purified

Immunogen: RELM alpha antibody was raised in rabbit using highly pure recombinant murine RELMa as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Referenzen für anti-RELM alpha Antikörper (ABIN636644)

Wang, Ismahil, Zhu, Rokosh, Hamid, Zhou, Pogwizd, Prabhu: "CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy." in: Circulation, Vol. 152, Issue 4, pp. 257-273, (2025) (PubMed).

Details zu RELM alpha

Target: RELM alpha

Hintergrund: RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown.

Molekulargewicht: 10.0 kDa (predicted detection band MW)