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RELM alpha Antikörper

Der Kaninchen Polyklonal Anti-RELM alpha-Antikörper wurde für WB, ELISA und Inhibition validiert. Er ist geeignet, RELM alpha in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN636644

Kurzübersicht für RELM alpha Antikörper (ABIN636644)

Target

Alle RELM alpha Antikörper anzeigen
RELM alpha

Reaktivität

  • 28
  • 17
  • 4
Maus

Wirt

  • 31
  • 2
  • 1
Kaninchen

Klonalität

  • 31
  • 3
Polyklonal

Konjugat

  • 13
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RELM alpha Antikörper ist unkonjugiert

Applikation

  • 34
  • 16
  • 13
  • 7
  • 2
Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)
  • Aufreinigung

    Purified

    Immunogen

    RELM alpha antibody was raised in rabbit using highly pure recombinant murine RELMa as the immunogen.
  • Applikationshinweise

    Optimal conditions should be determined byt he investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Konzentration

    Lot specific

    Buffer

    Lyophilized from PBS, pH 7.2.

    Handhabung

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
  • Wang, Ismahil, Zhu, Rokosh, Hamid, Zhou, Pogwizd, Prabhu: "CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy." in: Circulation, Vol. 152, Issue 4, pp. 257-273, (2025) (PubMed).

  • Target

    RELM alpha

    Hintergrund

    RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown.

    Molekulargewicht

    10.0 kDa (predicted detection band MW)
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