Follistatin Antikörper
Kurzübersicht für Follistatin Antikörper (ABIN636639)
Target
Alle Follistatin (FST) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified
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Immunogen
- Follistatin antibody was raised in rabbit using highly pure recombinant human Follistatin as the immunogen.
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Applikationshinweise
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ELISA: 0.5-2 µg/mL, Inhibition: 8-12 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- Follistatin (FST)
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Andere Bezeichnung
- Follistatin
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Hintergrund
- Follistatin is a secreted protein that binds to ligands of the TGF beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues.
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Molekulargewicht
- 31.5 kDa (predicted detection band MW)
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Pathways
- Negative Regulation of Hormone Secretion
Target
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