CLCF1 Antikörper

Produktnummer ABIN636624

Der Kaninchen Polyklonal anti-CLCF1 Antikörper (ABIN636624) detektiert spezifisch CLCF1 in WB, ELISA und InhibAb. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CLCF1 Antikörper (ABIN636624)

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Produktdetails anti-CLCF1 Antikörper

Aufreinigung: Purified

Immunogen: NNT1 antibody was raised in rabbit using highly pure recombinant human NNT-1/BCSF-3 as the immunogen.

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined byt he investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu CLCF1

Target: CLCF1 (Cardiotrophin-Like Cytokine Factor 1 (CLCF1))

Andere Bezeichnung: NNT1

Hintergrund: NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM.

Molekulargewicht: 22.4 kDa (predicted detection band MW)

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response