Kurzübersicht für CDC4 (69kDa) (N-Term) Antikörper (ABIN636265)
Target
CDC4 (69kDa)
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Applikation
Western Blotting (WB)
Bindungsspezifität
N-Term
Aufreinigung
Affinity chromatography purified
Immunogen
CDC4 (69 kDa) antibody was raised in rabbit using N terminus of the 69 kDa isoform of the hCdc4 protein as the immunogen.
Isotyp
IgG
Applikationshinweise
WB: 1:500-1:1,000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
Lot specific
Buffer
Affinity purified IgG supplied in PBS with 0.02 % NaN3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
CDC4 (69kDa)
Hintergrund
Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.