BRAF25 antikoerper, BRAF35 antikoerper, HMGX2 antikoerper, HMGXB2 antikoerper, PP7706 antikoerper, SMARCE1r antikoerper, SOXL antikoerper, pp8857 antikoerper, AW610687 antikoerper, Hmgx2 antikoerper, Hmgxb2 antikoerper, Smarce1r antikoerper, high mobility group 20 B antikoerper, high mobility group 20B antikoerper, Hmg20b antikoerper, HMG20B antikoerper
Hintergrund
Mutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35). There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression.