NOS1 Antikörper (AA 19-31)

Produktnummer ABIN636185

Der Kaninchen Polyklonal Anti-NOS1-Antikörper wurde für WB validiert. Er ist geeignet, NOS1 in Proben von Human zu detektieren.

Kurzübersicht für NOS1 Antikörper (AA 19-31) (ABIN636185)

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NOS1 Antikörper

Bindungsspezifität: AA 19-31

Aufreinigung: Affinity chromatography purified

Immunogen: nNOS antibody was raised in rabbit using AA 19-31 [PRKGPPLPNGDTEC] of NOS as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu NOS1

Target: NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))

Andere Bezeichnung: nNOS

Hintergrund: Human nitric oxide synthases are a family of enzymes responsible for the synthesis of nitric oxide from L-arginine and molecular oxygen. There are at least three nitric oxide synthases, NOS I, also known as neuronal NOS or nNOS, NOS II, which is referred to as inducible NOS or iNOS and NOS III, also known as endothelial NOS or eNOS. nNOS plays a role in the upregulation of microglial phospho-p38 MAPK. Such p38 MAPK activation in microglia is consistent with a potential role in the development of morphine antinociceptive tolerance.

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction