KDELR3 Antikörper
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- Target Alle KDELR3 (kDELR3) Antikörper anzeigen
- KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDELR3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purified
- Immunogen
- KDELR3 antibody was raised using a synthetic peptide corresponding to a region with amino acids AYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILW
- Top Product
- Discover our top product kDELR3 Primärantikörper
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- Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Kommentare
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KDELR3 Blocking Peptide, catalog no. 33R-1635, is also available for use as a blocking control in assays to test for specificity of this KDELR3 antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KDELR3 antibody in PBS
- Konzentration
- Lot specific
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))
- Andere Bezeichnung
- KDELR3 (kDELR3 Produkte)
- Hintergrund
- Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (kDaEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognises, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the kDaEL receptor gene family, have been described. kDaELR3 was the third member of the family to be identified, and it encodes a protein highly homologous to kDaELR1 and kDaELR2 proteins.
- Molekulargewicht
- 25 kDa (MW of target protein)
- Pathways
- ER-Nucleus Signaling, Maintenance of Protein Location
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