Fc epsilon RI/FCER1A Antikörper (N-Term)
Kurzübersicht für Fc epsilon RI/FCER1A Antikörper (N-Term) (ABIN635223)
Target
Alle Fc epsilon RI/FCER1A (FCER1A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- FCER1 A antibody was raised against the N terminal of FCER1
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Aufreinigung
- Affinity purified
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Immunogen
- FCER1 A antibody was raised using the N terminal of FCER1 corresponding to a region with amino acids NPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAK
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Applikationshinweise
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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FCER1A Blocking Peptide, ABIN5613559, is also available for use as a blocking control in assays to test for specificity of this FCER1A antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FCER0 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Andere Bezeichnung
- FCER1A
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Hintergrund
- The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule.
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Molekulargewicht
- 27 kDa (MW of target protein)
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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