FBXW7 Antikörper (C-Term)

Produktnummer ABIN635114

Der Kaninchen Polyklonal Anti-FBXW7-Antikörper wurde für WB validiert. Er ist geeignet, FBXW7 in Proben von Human, Maus und Drosophila melanogaster zu detektieren.

Kurzübersicht für FBXW7 Antikörper (C-Term) (ABIN635114)

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Reaktivität: Human, Maus, Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXW7 Antikörper

Bindungsspezifität: C-Term

Spezifität: FBXW7 antibody was raised against the C terminal of FBXW7

Aufreinigung: Affinity purified

Immunogen: FBXW7 antibody was raised using the C terminal of FBXW7 corresponding to a region with amino acids LKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVL

Anwendungsinformationen

Applikationshinweise: WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

FBXW7 Blocking Peptide, (ABIN940494), is also available for use as a blocking control in assays to test for specificity of this FBXW7 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FBXW7 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu FBXW7

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Andere Bezeichnung: FBXW7

Hintergrund: FBXW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.

Molekulargewicht: 66 kDa (MW of target protein)

Pathways: Notch Signalweg, EGFR Signaling Pathway