SH3RF1 Antikörper (Middle Region)

Produktnummer ABIN631195

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SH3RF1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SH3RF1 Antikörper (Middle Region) (ABIN631195)

Target: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SH3RF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SH3RF1 Antikörper

Bindungsspezifität: Middle Region

Spezifität: SH3 RF1 antibody was raised against the middle region of SH3 F1

Aufreinigung: Affinity purified

Immunogen: SH3 RF1 antibody was raised using the middle region of SH3 F1 corresponding to a region with amino acids LLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPPGGGHG

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SH3RF1 Blocking Peptide, (ABIN940541), is also available for use as a blocking control in assays to test for specificity of this SH3RF1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SH0 F1 antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu SH3RF1

Target: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Andere Bezeichnung: SH3RF1

Hintergrund: SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Molekulargewicht: 93 kDa (MW of target protein)