HAAO Antikörper (N-Term)

Produktnummer ABIN631165

Produktdetails anti-HAAO Antikörper

Target: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAAO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: HAAO antibody was raised against the N terminal of HAAO

Aufreinigung: Affinity purified

Immunogen: HAAO antibody was raised using the N terminal of HAAO corresponding to a region with amino acids HRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYVG

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

HAAO Blocking Peptide, catalog no. 33R-3836, is also available for use as a blocking control in assays to test for specificity of this HAAO antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAAO antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu HAAO

Target: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Andere Bezeichnung: HAAO (HAAO Produkte)

Synonyme: Afu2g17450 antikoerper, 0610007K21Rik antikoerper, 0610012J07Rik antikoerper, 3-HAO antikoerper, 3-HAOxase antikoerper, 3HAO antikoerper, zgc:103585 antikoerper, HAO antikoerper, 3-hydroxyanthranilate 3,4-dioxygenase antikoerper, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog antikoerper, SPO1774 antikoerper, CNB05620 antikoerper, AFUA_2G17450 antikoerper, Bcep18194_C7641 antikoerper, Kfla_5491 antikoerper, Micau_4935 antikoerper, RBRH_03005 antikoerper, Krodi_1278 antikoerper, haao antikoerper, HAAO antikoerper, Haao antikoerper, haao.L antikoerper

Hintergrund: 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.

Molekulargewicht: 32 kDa (MW of target protein)