Gephyrin Antikörper (Middle Region)

Produktnummer ABIN630878

Der Kaninchen Polyklonal Anti-Gephyrin-Antikörper wurde für WB validiert. Er ist geeignet, Gephyrin in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Gephyrin Antikörper (Middle Region) (ABIN630878)

Target: Gephyrin (GPHN)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gephyrin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Gephyrin Antikörper

Bindungsspezifität: Middle Region

Spezifität: Gephyrin antibody was raised against the middle region of GPHN

Aufreinigung: Affinity purified

Immunogen: Gephyrin antibody was raised using the middle region of GPHN corresponding to a region with amino acids GEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEV

Anwendungsinformationen

Applikationshinweise: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Gephyrin Blocking Peptide, catalog no. 33R-3243, is also available for use as a blocking control in assays to test for specificity of this Gephyrin antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GPHN antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu Gephyrin

Target: Gephyrin (GPHN)

Andere Bezeichnung: Gephyrin

Hintergrund: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Molekulargewicht: 80 kDa (MW of target protein)

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development