DDOST Antikörper (N-Term)
Kurzübersicht für DDOST Antikörper (N-Term) (ABIN630468)
Target
Alle DDOST Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- DDOST antibody was raised against the N terminal of DDOST
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Aufreinigung
- Purified
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Immunogen
- DDOST antibody was raised using the N terminal of DDOST corresponding to a region with amino acids SPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFD
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Applikationshinweise
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WB: 5 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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DDOST Blocking Peptide, catalog no. 33R-8698, is also available for use as a blocking control in assays to test for specificity of this DDOST antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DDOST antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
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Andere Bezeichnung
- DDOST
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Hintergrund
- DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
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Molekulargewicht
- 46 kDa (MW of target protein)
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Pathways
- Cell RedoxHomeostasis
Target
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