IL-10RA Antikörper (N-Term)

Produktnummer ABIN630438

Dieses Anti-IL-10RA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL-10RA in WB. Geeignet für Human.

Kurzübersicht für IL-10RA Antikörper (N-Term) (ABIN630438)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-10RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-10RA Antikörper

Bindungsspezifität: N-Term

Spezifität: IL10 R Alpha antibody was raised against the N terminal of IL10 A

Aufreinigung: Purified

Immunogen: IL10 R Alpha antibody was raised using the N terminal of IL10 A corresponding to a region with amino acids GSVNLEIHNGFILGKIQLPRPKMAPANDTYESIFSHFREYEIAIRKVPGN

Anwendungsinformationen

Applikationshinweise: WB: 5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

IL10R Alpha Blocking Peptide, (ABIN938981), is also available for use as a blocking control in assays to test for specificity of this IL10R Alpha antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL10 A antibody in PBS

Konzentration: Lot specific

Buffer: PBS

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Details zu IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Andere Bezeichnung: IL10R alpha

Hintergrund: IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.

Molekulargewicht: 61 kDa (MW of target protein)

Pathways: Growth Factor Binding