Ube2t Antikörper
Kurzübersicht für Ube2t Antikörper (ABIN6298352)
Target
Alle Ube2t Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- Rabbit Anti-UBE2T Antibody,
-
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
-
-
- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
-
Andere Bezeichnung
- UBE2T
-
Hintergrund
-
Target Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.
Gene Symbol: UBE2T
-
Gen-ID
- 29089
-
UniProt
- Q9NPD8
-
Pathways
- Chromatin Binding
Target
-