ERI1 Antikörper

Produktnummer ABIN6298170

Dieses Anti-ERI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ERI1 in . Geeignet für Human, Maus und Ratte.

Kurzübersicht für ERI1 Antikörper (ABIN6298170)

Target: ERI1 (Exoribonuclease 1 (ERI1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERI1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-ERI1 Antikörper

Verwendungszweck: Rabbit Anti-ERI1 Antibody,

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ERI1

Target: ERI1 (Exoribonuclease 1 (ERI1))

Andere Bezeichnung: ERI1

Hintergrund:

Target Description: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication- dependent histone pre-mRNAs.

Gene Symbol: ERI1

Gen-ID: 90459

UniProt: Q8IV48