PAWR Antikörper

Produktnummer ABIN6298166

Produktdetails anti-PAWR Antikörper

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAWR Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Verwendungszweck: Rabbit Anti-Prostate Apoptosis Response protein-4 Antibody,

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PAWR

Target: PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Andere Bezeichnung: Prostate Apoptosis Response protein-4 (PAWR Produkte)

Synonyme: MGC81382 antikoerper, pawrl antikoerper, zgc:103513 antikoerper, PAWR antikoerper, PAR4 antikoerper, Par-4 antikoerper, Par4 antikoerper, 2310001G03Rik antikoerper, pro-apoptotic WT1 regulator antikoerper, PRKC, apoptosis, WT1, regulator L homeolog antikoerper, PRKC, apoptosis, WT1, regulator antikoerper, PAWR antikoerper, pawr.L antikoerper, pawr antikoerper, Pawr antikoerper

Hintergrund:

Target Description: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.

Gene Symbol: PAWR

Gen-ID: 5074

UniProt: Q96IZ0