USP5 Antikörper

Produktnummer ABIN6297889

Produktdetails anti-USP5 Antikörper

Target: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser USP5 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Verwendungszweck: Mouse Anti-USP5 Antibody

Immunogen: This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu USP5

Target: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Andere Bezeichnung: USP5 (USP5 Produkte)

Synonyme: ISOT antikoerper, AA407472 antikoerper, ISOT-1 antikoerper, Ucht antikoerper, ubiquitin specific peptidase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5, putative antikoerper, ubiquitin specific protease 5 antikoerper, ubiquitin specific peptidase 5 (isopeptidase T) antikoerper, USP5 antikoerper, CNH02890 antikoerper, EHI_049940 antikoerper, CC1G_12961 antikoerper, MCYG_01862 antikoerper, CGB_L3600C antikoerper, PY00546 antikoerper, Usp5 antikoerper

Hintergrund:

Target Description: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Gene Symbol: USP5

Gen-ID: 8078

UniProt: P45974