PPARA Antikörper
Kurzübersicht für PPARA Antikörper (ABIN6297876)
Target
Alle PPARA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse Anti-PPARA Antibody
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Immunogen
- This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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Andere Bezeichnung
- PPARA
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Hintergrund
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Target Description: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Gene Symbol: PPARA
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Gen-ID
- 5465
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UniProt
- Q07869
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
Target
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