PGC Antikörper (Biotin)

Produktnummer ABIN6297820

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PGC in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PGC Antikörper (Biotin) (ABIN6297820)

Target: PGC (Pepsinogen C (PGC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGC Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Klon: 4A3-G4-G6

Produktdetails anti-PGC Antikörper (Biotin)

Verwendungszweck: Mouse anti-Human PGC Biotinylated Antibody

Immunogen: This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: -20°C

Details zu PGC

Target: PGC (Pepsinogen C (PGC))

Andere Bezeichnung: PGC

Hintergrund:

Target Description: PGC gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

UniProt: P20142