CA9 Antikörper

Produktnummer ABIN6297756

Dieses Anti-CA9-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CA9 in IHC. Geeignet für Human und Pferd.

Kurzübersicht für CA9 Antikörper (ABIN6297756)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reaktivität: Human, Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CA9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-CA9 Antikörper

Verwendungszweck: Mouse anti-Human/Horse Carbonic Anhydrase 9 Antibody [IHC only]

Spezifität: Cell surface and cytoplasmic

Aufreinigung: The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for the Carbonic Anhydrase 9 antibody.

Immunogen: The microsomal fraction of human renal cortical tissue homogenate was used as the immunogen for the Carbonic Anhydrase 9 antibody.

Anwendungsinformationen

Applikationshinweise: Prediluted format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Andere Bezeichnung: Carbonic anhydrase 9

Hintergrund:

Target Description: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/CA9/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This mAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Gene Symbol: CA9///G250///MN

Gen-ID: 768

UniProt: Q16790