RNMT Antikörper

Produktnummer ABIN6297755

Produktdetails anti-RNMT Antikörper

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RNMT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Verwendungszweck: Mouse anti-Human/Cow/Dog/Hamster/Rat TAG-72 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic and cell surface

Aufreinigung: The membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Immunogen: The membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu RNMT

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Andere Bezeichnung: mRNA cap guanine-N7 methyltransferase   (RNMT Produkte)

Hintergrund:

Target Description: This antibody recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of TAG-72 Ab with a GCDFP-15 Ab is valuable in the diagnosis of apocrine carcinoma.

Gene Symbol: tag-72  C25A1.3

Gen-ID: 182875

UniProt: Q9XVS1