CD20 Antikörper (PE)

Produktnummer ABIN6297750

Dieses Anti-CD20-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD20 in FACS, IF und T. Geeignet für Human.

Kurzübersicht für CD20 Antikörper (PE) (ABIN6297750)

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD20 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Produktdetails anti-CD20 Antikörper (PE)

Verwendungszweck: Mouse anti-Human CD20 Antibody [PE Conjugated]

Spezifität: Predominantly cell surface with some cytoplasmic

Aufreinigung: The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.

Immunogen: The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 5 µL per test per one million cells in 0.1 mL (or 5 µL per 100 µL of whole blood)
Immunofluorescence: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C. The conjugate is light-sensitive, protect from light.

Details zu CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Andere Bezeichnung: B-lymphocyte antigen CD20

Hintergrund:

Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

Gene Symbol: MS4A1///CD20

Gen-ID: 931

UniProt: P11836