PTH Antikörper
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- Target Alle PTH Antikörper anzeigen
- PTH (Parathyroid Hormone (PTH))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PTH Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Verwendungszweck
- Mouse anti-Human PTH Antibody Cocktail [IHC only]
- Spezifität
- Cytoplasmic and secreted
- Aufreinigung
- Synthetic peptides corresponding to amino acids 1 to 34 (clone 3H9) and 32-115 (clone PTH/1175) were used as the immunogen for the PTH antibody cocktail.
- Immunogen
- Synthetic peptides corresponding to amino acids 1 to 34 (clone 3H9) and 32-115 (clone PTH/1175) were used as the immunogen for the PTH antibody cocktail.
- Top Product
- Discover our top product PTH Primärantikörper
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- Applikationshinweise
- Prediluted format : incubate for 30 min at RT (2)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- PTH (Parathyroid Hormone (PTH))
- Andere Bezeichnung
- Parathyroid hormone (PTH Produkte)
- Synonyme
- PTH1 antikoerper, Pthp antikoerper, PTH-(1-84) antikoerper, Pth1 antikoerper, Pthr1 antikoerper, PTH antikoerper, parathyroid hormone antikoerper, parathyroid hormone S homeolog antikoerper, PTH antikoerper, Pth antikoerper, pth.S antikoerper
- Substanzklasse
- Hormone
- Hintergrund
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Target Description: PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Gene Symbol: PTH
- Gen-ID
- 5741
- UniProt
- P01270
- Pathways
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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