IGKV1D-16 Antikörper

Produktnummer ABIN6297706

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IGKV1D-16 in IHC, FACS und WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IGKV1D-16 Antikörper (ABIN6297706)

Target: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGKV1D-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB)

Produktdetails anti-IGKV1D-16 Antikörper

Verwendungszweck: Mouse anti-Human Kappa Light Chain Antibody [Sodium Azide Free]

Spezifität: Cell surface, cytoplasmic and secreted

Aufreinigung: Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.

Immunogen: Stimulated human lymphocytes were used as the immunogen for the Kappa Light Chain antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-2.0 μg/million cells in 0.1ml
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu IGKV1D-16

Target: IGKV1D-16 (Immunoglobulin kappa Variable 1D-16 (IGKV1D-16))

Andere Bezeichnung: Immunoglobulin kappa variable 1D-16

Hintergrund:

Target Description: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Gene Symbol: IGKV1D-16///IGKC

Gen-ID: 3514

UniProt: P01601, P01834