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CD43 Antikörper

SPN Reaktivität: Human IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297681
  • Target Alle CD43 (SPN) Antikörper anzeigen
    CD43 (SPN) (Sialophorin (SPN))
    Reaktivität
    • 159
    • 29
    • 10
    Human
    Wirt
    • 96
    • 74
    • 23
    Maus
    Klonalität
    • 107
    • 85
    • 1
    Monoklonal
    Konjugat
    • 68
    • 20
    • 20
    • 19
    • 15
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD43 Antikörper ist unkonjugiert
    Applikation
    • 105
    • 101
    • 66
    • 62
    • 42
    • 19
    • 18
    • 14
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Verwendungszweck
    Mouse anti-Human CD43 Antibody [IHC only]
    Spezifität
    Cell surface
    Aufreinigung
    Stimulated human leukocytes were used as the immunogen for the CD43 antibody.
    Immunogen
    Stimulated human leukocytes were used as the immunogen for the CD43 antibody.
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  • Applikationshinweise
    Prediluted format : incubate for 30 min at RT (2)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    CD43 (SPN) (Sialophorin (SPN))
    Andere Bezeichnung
    Leukosialin (SPN Produkte)
    Synonyme
    CD43 antikoerper, GALGP antikoerper, GPL115 antikoerper, LSN antikoerper, A630014B01Rik antikoerper, Cd43 antikoerper, Galgp antikoerper, Ly-48 antikoerper, Ly48 antikoerper, Lsn antikoerper, Lsn1 antikoerper, gpL115 antikoerper, sialophorin antikoerper, SPN antikoerper, Spn antikoerper
    Hintergrund

    Target Description: It recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90 % of T-cell lymphomas and from 22-37 % of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

    Gene Symbol: SPN///CD43

    Gen-ID
    6693
    UniProt
    P16150
    Pathways
    Regulation of Leukocyte Mediated Immunity
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