Cytokeratin 1 Antikörper

Produktnummer ABIN6297656

Der Maus Monoklonal Anti-Cytokeratin 1-Antikörper wurde für WB, IHC, FACS und IF validiert. Er ist geeignet, Cytokeratin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Cytokeratin 1 Antikörper (ABIN6297656)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Cytokeratin 1 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat HMW Cytokeratin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.

Immunogen: Solubilized keratin extract from human stratum corneum was used as the immunogen for this HMW Cytokeratin antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10e6 cells
IF: 0.5-1.0 μg/mL
WB: 0.5-1.0 μg/mL
IHC (FFPE): 0.5-1.0 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Andere Bezeichnung: Keratin, type II cytoskeletal 1

Hintergrund:

Target Description: This antibody recognizes HMW Keratin 1, 5, 10 and 14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. The HMW Cytokeratin antibody shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this mAb. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. It has also been useful in separating benign from malignant intraductal breast proliferations.

Gene Symbol: KRT1///KRTA

Gen-ID: 3848

UniProt: P04264