Keratin 10 Antikörper

Produktnummer ABIN6297653

Der Maus Monoklonal Anti-Keratin 10-Antikörper wurde für IHC, WB, FACS und IF validiert. Er ist geeignet, Keratin 10 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Affe, Rind (Kuh), Huhn und Schildkröte zu detektieren.

Kurzübersicht für Keratin 10 Antikörper (ABIN6297653)

Target: Keratin 10 (KRT10)

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Affe, Rind (Kuh), Huhn, Schildkröte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Keratin 10 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Keratin 10 Antikörper

Verwendungszweck: Mouse anti-Human/Monkey/Cow/Dog/Rabbit/Mouse/Rat/Chicken/Turtle Acidic Cytokeratin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Solubilized keratin extract from human stratum corneum

Immunogen: Solubilized keratin extract from human stratum corneum

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Keratin 10

Target: Keratin 10 (KRT10)

Andere Bezeichnung: Keratin, type I cytoskeletal 10

Hintergrund:

Target Description: Cytokeratins, also called keratins or simply CKs, are a family of fibrous structural proteins and a major structural component in the outer layer of human skin, as well as hair and nails.  There are 20 human epithelial keratins which can be divided into two subfamiles: acidic and basic (more recent human genone sequencing has identified an additional 20 members). The formation of cytokeratin intermediate filaments requires the pairing of at least one acidic and one basic subfamily member. Members of the same keratin subfamily share extended sequence homology while members of different subfamilies show only limited sequence homology.This antibody is specific for the 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), and 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Many studies have shown the usefulness of CKs as markers in cancer research and tumor diagnosis, as epithelial tumors generally maintain the same CK expression patterns as their counterpart normal tissue. Clone AE1 is commonly used with clone AE3 as a pan cytokeratin antibody cocktail (< a href=../pan-cytokeratin-antibody-cocktail-ae1-ae3-v2330>Cat No V2330).

Gene Symbol: KRT10///KPP

Gen-ID: 3858

UniProt: P13645