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TYR Antikörper

TYR Reaktivität: Human IF, IHC, FACS Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297626
  • Target Alle TYR Antikörper anzeigen
    TYR (Tyrosinase (TYR))
    Reaktivität
    • 91
    • 23
    • 20
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 37
    Maus
    Klonalität
    • 47
    • 46
    Monoklonal
    Konjugat
    • 54
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TYR Antikörper ist unkonjugiert
    Applikation
    • 50
    • 39
    • 28
    • 27
    • 24
    • 20
    • 18
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]
    Spezifität
    Cytoplasmic
    Aufreinigung
    Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
    Immunogen
    Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
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  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    TYR (Tyrosinase (TYR))
    Andere Bezeichnung
    Tyrosinase (TYR Produkte)
    Synonyme
    sandy antikoerper, zgc:109705 antikoerper, TYR antikoerper, TYRO antikoerper, tyr antikoerper, LOC100136546 antikoerper, CMM8 antikoerper, OCA1A antikoerper, OCAIA antikoerper, SHEP3 antikoerper, albino antikoerper, c antikoerper, skc35 antikoerper, C antikoerper, tyrosinase antikoerper, TYRosinase antikoerper, tyrosinase S homeolog antikoerper, tyr antikoerper, tyr-5 antikoerper, tyr.S antikoerper, TYR antikoerper, Celal_3121 antikoerper, Halhy_4121 antikoerper, Mesop_2736 antikoerper, LOC100136546 antikoerper, Tyr antikoerper
    Hintergrund

    Target Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.

    Gene Symbol: TYR

    Gen-ID
    7299
    UniProt
    P14679
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